A General Diastereoselective Catalytic Vinylogous Aldol Reaction Among Tetramic Acid-Derived Pyrroles
- Degree Grantor:
- University of California, Santa Barbara. Chemistry
- Degree Supervisor:
- Thomas R R Pettus
- Place of Publication:
- [Santa Barbara, Calif.]
- Publisher:
- University of California, Santa Barbara
- Creation Date:
- 2015
- Issued Date:
- 2015
- Topics:
- Organic chemistry
- Keywords:
- Tetramic,
Pyrrole,
Aldol, and
Diastereoselective - Genres:
- Online resources and Dissertations, Academic
- Dissertation:
- M.S.--University of California, Santa Barbara, 2015
- Description:
A catalytic diastereoselective aldol reaction has been developed for N1-arylated/C2-O-silylated/C3-methylated and brominated/C4-O-methylated pyrroles in its reactions with various aldehydes. Syn adducts emerge with regard to the vicinal nitrogen and oxygen heteroatom substituents. The N1-aryl residue undergoes oxidative cleavage, and the C3- bromine atom undergoes palladium-mediated coupling reactions, both without disturbing the newly created stereocenters.
- Physical Description:
- 1 online resource (35 pages)
- Format:
- Text
- Collection(s):
- UCSB electronic theses and dissertations
- Other Versions:
- http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:dissertation&res_dat=xri:pqm&rft_dat=xri:pqdiss:1603381
- ARK:
- ark:/48907/f31v5c5d
- ISBN:
- 9781339218854
- Catalog System Number:
- 990045865210203776
- Copyright:
- Jonathan David, 2015
- Rights:
- In Copyright
- Copyright Holder:
- Jonathan David
File | Description |
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Access: Public access | |
David_ucsb_0035N_12734.pdf | pdf (Portable Document Format) |